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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Russian Journal of Dentistry</journal-id><journal-title-group><journal-title xml:lang="en">Russian Journal of Dentistry</journal-title><trans-title-group xml:lang="ru"><trans-title>Российский стоматологический журнал</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1728-2802</issn><issn publication-format="electronic">2413-2934</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">321847</article-id><article-id pub-id-type="doi">10.17816/dent321847</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Experimental and Theoretical Investigations</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Экспериментально-теоретические исследования</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">Experimental and clinical substantiation of the combined use of resin infiltrate and flowable composite material in minimally invasive treatment of dental fluorosis</article-title><trans-title-group xml:lang="ru"><trans-title>Экспериментально-клиническое обоснование сочетанного использования инфильтранта и низкомодульного композитного материала при минимально инвазивном лечении флюороза зубов</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-9881-6574</contrib-id><name-alternatives><name xml:lang="en"><surname>Tiunova</surname><given-names>Natalia V.</given-names></name><name xml:lang="ru"><surname>Тиунова</surname><given-names>Наталья Викторовна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Medicine), Associate Professor</p></bio><bio xml:lang="ru"><p>д-р мед. наук, доцент</p></bio><email>natali5_@list.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0499-3487</contrib-id><name-alternatives><name xml:lang="en"><surname>Naberezhnova</surname><given-names>Svetlana S.</given-names></name><name xml:lang="ru"><surname>Набережнова</surname><given-names>Светлана Сергеевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><email>natali5_@list.ru</email><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0003-0085-1051</contrib-id><contrib-id contrib-id-type="spin">2887-0074</contrib-id><name-alternatives><name xml:lang="en"><surname>Daurova</surname><given-names>Fatima Yu.</given-names></name><name xml:lang="ru"><surname>Даурова</surname><given-names>Фатима Юрьевна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Dr. Sci. (Medicine), Professor</p></bio><bio xml:lang="ru"><p>д-р мед. наук, профессор</p></bio><email>5071098@mail.ru</email><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><contrib-id contrib-id-type="orcid">https://orcid.org/0000-0001-8771-2438</contrib-id><name-alternatives><name xml:lang="en"><surname>Tomaeva</surname><given-names>Diana I.</given-names></name><name xml:lang="ru"><surname>Томаева</surname><given-names>Диана Исланбековна</given-names></name></name-alternatives><address><country country="RU">Russian Federation</country></address><bio xml:lang="en"><p>MD, Cand. Sci. (Medicine), Associate Professor</p></bio><bio xml:lang="ru"><p>канд. мед. наук, доцент</p></bio><email>tomaevad@inbox.ru</email><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Volga Research Medical University</institution></aff><aff><institution xml:lang="ru">Приволжский исследовательский медицинский университет</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Synergy University</institution></aff><aff><institution xml:lang="ru">Университет «Синергия»</institution></aff></aff-alternatives><pub-date date-type="preprint" iso-8601-date="2024-07-03" publication-format="electronic"><day>03</day><month>07</month><year>2024</year></pub-date><pub-date date-type="pub" iso-8601-date="2024-08-09" publication-format="electronic"><day>09</day><month>08</month><year>2024</year></pub-date><volume>28</volume><issue>3</issue><issue-title xml:lang="en"/><issue-title xml:lang="ru"/><fpage>253</fpage><lpage>260</lpage><history><date date-type="received" iso-8601-date="2024-04-04"><day>04</day><month>04</month><year>2024</year></date><date date-type="accepted" iso-8601-date="2024-08-01"><day>01</day><month>08</month><year>2024</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2024, Eco-Vector</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2024, Эко-Вектор</copyright-statement><copyright-year>2024</copyright-year><copyright-holder xml:lang="en">Eco-Vector</copyright-holder><copyright-holder xml:lang="ru">Эко-Вектор</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/" start_date="2027-08-09"/><license><ali:license_ref xmlns:ali="http://www.niso.org/schemas/ali/1.0/">https://creativecommons.org/licenses/by-nc-nd/4.0</ali:license_ref></license></permissions><self-uri xlink:href="https://rjdentistry.com/1728-2802/article/view/321847">https://rjdentistry.com/1728-2802/article/view/321847</self-uri><abstract xml:lang="en"><p><bold>BACKGROUND:</bold> To eliminate white spots in dental fluorosis, methods of remineralizing therapy, microabrasion, and infiltration are currently used, which have special features in this pathology because of the deep location of the hypomineralization zone.</p> <p><bold>AIM:</bold> To study the adhesive strength of a fluid composite filling material to the infiltrate ICON and tooth enamel in fluorosis and evaluate the results of the combined use of resin infiltration and composite material in the clinic.</p> <p><bold>MATERIALS AND METHODS:</bold> Adhesive tear strength tests of various materials were performed on 60 extracted teeth with fluorosis, such as lesions in the form of white spots. By random sampling, teeth with fluorosis were divided into four groups of 15 teeth each. To induce a defect that allowed for the study of adhesive strength using a sandblaster (Rondoflex, CAVO, Germany), an aluminum oxide powder with a particle size of 27 microns at a distance of 1 cm was treated in the center of the vestibular surface for 3 s.</p> <p><bold>RESULTS:</bold> The best indicators of adhesive tear strength were obtained using a universal adhesive system and a low-modulus composite material and combining an infiltrant and a low-modulus composite material containing a 10-methacryloyloxydecyl dihydrogen phosphate (MDP) monomer. The results of the experimental study indicated that the combination of an infiltrate and a low-modulus composite material based on MDP monomer can be a promising option in the minimally invasive treatment of dental fluorosis in the clinic. After the treatment following the previously described scheme, the examination after 1 month did not reveal disruption of the marginal fit and staining of the border and secondary caries; however, one case of sensitivity was noted. Upon examination after 1 year, no cases of violation of the marginal fit, development of caries along the boundaries of the treatment, and sensitivity were observed.</p> <p><bold>CONCLUSION:</bold> The results of the experimental clinical study indicated the high effectiveness of minimally invasive dental fluorosis treatment using a combination of infiltration and low-modulus composite material based on MDP monomer.</p></abstract><trans-abstract xml:lang="ru"><p><bold>Обоснование.</bold> Для устранения белых пятен при флюорозе зубов на сегодняшний день применяются методики реминерализирующей терапии, микроабразии и инфильтрации, которые не лишены некоторых особенностей проведения при данной патологии вследствие глубокого расположения зоны гипоминерализации.</p> <p><bold>Цель исследования </bold>—<bold> </bold>изучение адгезионной прочности инфильтранта и низкомодульного композитного материала при флюорозе зубов в эксперименте, а также оценка ближайших и отдалённых результатов проведённого лечения в клинике.</p> <p><bold>Материалы и методы.</bold> Изучение адгезионной прочности на отрыв при применении различных материалов проведено на 60 удалённых зубах с флюорозом (поражения в виде пятен белого цвета). Методом случайной выборки зубы с флюорозом были разделены на 4 группы по 15 зубов в каждой. Для формирования дефекта с целью изучения адгезионной прочности проводили обработку в центре вестибулярной поверхности порошком на основе оксида алюминия с размером частиц 27 мк на расстоянии 1 см в течение 3 с.</p> <p><bold>Результаты.</bold> Наилучшие показатели адгезионной прочности на отрыв получены при применении универсальной адгезивной системы и низкомодульного композитного материала, а также при сочетании применения инфильтранта и низкомодульного композитного материала, содержащего МDP-мономер. Полученные в экспериментальном исследовании результаты позволили рассмотреть сочетание инфильтранта и низкомодульного композитного материала на основе МDP-мономера, как перспективный вариант для применения в клинике при минимально инвазивном лечении флюороза зубов. После проведённого лечения по ранее описанной схеме при осмотре через 1 мес не было выявлено нарушения краевого прилегания, окрашивания границы и вторичного кариеса, отмечен 1 случай чувствительности. При осмотре через 1 год не наблюдали нарушения краевого прилегания и развития кариеса по границам проведённого лечения и не отмечено случаев развития чувствительности.</p> <p><bold>Заключение. </bold>Результаты проведённого экспериментального клинического исследования свидетельствуют о высокой эффективности минимально инвазивного лечения флюороза зубов с применением сочетания инфильтрации и низкомодульного композитного материала на основе MDP-мономера.</p></trans-abstract><kwd-group xml:lang="en"><kwd>dental fluorosis</kwd><kwd>white spots</kwd><kwd>infiltration</kwd><kwd>flowable composite material</kwd><kwd>MDP monomer</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>флюороз зубов</kwd><kwd>белые пятна</kwd><kwd>инфильтрация</kwd><kwd>низкомодульный композитный материал</kwd><kwd>MDP-мономер</kwd></kwd-group><funding-group/></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><citation-alternatives><mixed-citation xml:lang="en">Apolihin OI, sevryukov FA, Sorokin DA, et al. 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