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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Russian Journal of Dentistry</journal-id><journal-title-group><journal-title xml:lang="en">Russian Journal of Dentistry</journal-title><trans-title-group xml:lang="ru"><trans-title>Российский стоматологический журнал</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1728-2802</issn><issn publication-format="electronic">2413-2934</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">39175</article-id><article-id pub-id-type="doi">10.17816/dent.39175</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">INFLUENCE OF THE TYPE OF DENTAL PROSTHESIS ON THE LEVEL OF BIOMARKERS OF THE SALIVARY FLUID OF PATIENTS WITH ACQUIRED DEFECTS OF THE MAXILLA-FACIAL AREA</article-title><trans-title-group xml:lang="ru"><trans-title>ВЛИЯНИЕ ВИДА КОНСТРУКЦИИ СТОМАТОЛОГИЧЕСКОГО ПРОТЕЗА НА УРОВЕНЬ БИОМАРКЕРОВ РОТОВОЙ ЖИДКОСТИ У ПАЦИЕНТОВ С ПРИОБРЕТЕННЫМИ ДЕФЕКТАМИ ЧЕЛЮСТНО-ЛИЦЕВОЙ ОБЛАСТИ</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kochurova</surname><given-names>E. V</given-names></name><name xml:lang="ru"><surname>Кочурова</surname><given-names>Е. В</given-names></name></name-alternatives><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kozlov</surname><given-names>S. V</given-names></name><name xml:lang="ru"><surname>Козлов</surname><given-names>С. В</given-names></name></name-alternatives><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Nikolenko</surname><given-names>V. N</given-names></name><name xml:lang="ru"><surname>Николенко</surname><given-names>В. Н</given-names></name></name-alternatives><xref ref-type="aff" rid="aff1"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Gujter</surname><given-names>O. S</given-names></name><name xml:lang="ru"><surname>Гуйтер</surname><given-names>О. С</given-names></name></name-alternatives><xref ref-type="aff" rid="aff1"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">I.M. Sechenov First Moscow State Medical University</institution></aff><aff><institution xml:lang="ru">ГБОУ ВПО Первый МГМУ им. И.М. Сеченова Минздрава РФ</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2013-10-15" publication-format="electronic"><day>15</day><month>10</month><year>2013</year></pub-date><volume>17</volume><issue>5</issue><issue-title xml:lang="en">NO5 (2013)</issue-title><issue-title xml:lang="ru">№5 (2013)</issue-title><fpage>32</fpage><lpage>34</lpage><history><date date-type="received" iso-8601-date="2020-07-21"><day>21</day><month>07</month><year>2020</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2013, Eco-Vector</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2013, ООО "Эко-Вектор"</copyright-statement><copyright-year>2013</copyright-year><copyright-holder xml:lang="en">Eco-Vector</copyright-holder><copyright-holder xml:lang="ru">ООО "Эко-Вектор"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/></permissions><self-uri xlink:href="https://rjdentistry.com/1728-2802/article/view/39175">https://rjdentistry.com/1728-2802/article/view/39175</self-uri><abstract xml:lang="en"><p>Maxillofacial tumors have different localization, size, depth, but even the non-extent of pathology leads to the surround surgical procedures that even more leads to severe dysfunction and acquired defects of maxilla-facial area. Changes in the level of biomarkers of matrix metalloproteinases and tissue inhibitor of metalloproteinases actively used in the study of dental caries, periodontal diseases, as well as changes in traumatic and inflammatory Genesis, but unknown impact of the type of design dental prosthesis on changes in the level of this tipe markers.</p></abstract><trans-abstract xml:lang="ru"><p>Новообразования челюстно-лицевой области (ЧЛО) имеют различную локализацию, размеры, глубину, но даже небольшая по размерам патология приводит к объемным хирургическим вмешательствам, что в еще большей степени влечет выраженные дисфункции и приобретенные дефекты ЧЛО. Изменения уровня биомаркеров матриксных металлопротеиназ и их тканевых ингибиторов активно используется при изучении кариеса, заболеваниях пародонта, а также при изменениях травматического и воспалительного генеза, но неизвестно влияние вида конструкции стоматологического протеза на изменение уровня данной группы маркеров.</p></trans-abstract><kwd-group xml:lang="en"><kwd>Prosthetic Rehabilitation</kwd><kwd>biomarker</kwd><kwd>tumor</kwd><kwd>acquired defect</kwd><kwd>maxilla-facial area</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>ортопедическая реабилитация</kwd><kwd>биомаркер</kwd><kwd>новообразование</kwd><kwd>приобретенный дефект</kwd><kwd>челюстнолицевая область</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Чиссов В.И., Старинский В.В., Петрова Г.В. Состояние онкологической помощи населению России в 2011 году. М.: ФГБУ «МНИОИ им. П.А. 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