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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xmlns:ali="http://www.niso.org/schemas/ali/1.0/" article-type="research-article" dtd-version="1.2" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher-id">Russian Journal of Dentistry</journal-id><journal-title-group><journal-title xml:lang="en">Russian Journal of Dentistry</journal-title><trans-title-group xml:lang="ru"><trans-title>Российский стоматологический журнал</trans-title></trans-title-group></journal-title-group><issn publication-format="print">1728-2802</issn><issn publication-format="electronic">2413-2934</issn><publisher><publisher-name xml:lang="en">Eco-Vector</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">42188</article-id><article-id pub-id-type="doi">10.18821/1728-2802-2018-22-5-220-223</article-id><article-categories><subj-group subj-group-type="toc-heading" xml:lang="en"><subject>Articles</subject></subj-group><subj-group subj-group-type="toc-heading" xml:lang="ru"><subject>Статьи</subject></subj-group><subj-group subj-group-type="article-type"><subject>Research Article</subject></subj-group></article-categories><title-group><article-title xml:lang="en">THE USE OF RAMAN FLUORESCENCE TECHNOLOGY TO EVALUATE THE EFFECTIVENESS OF REMINERALIZATION OF SOLID TOOTH TISSUE</article-title><trans-title-group xml:lang="ru"><trans-title>ПРИМЕНЕНИЕ РАМАН-ФЛЮОРЕСЦЕНТНОЙ ТЕХНОЛОГИИ ДЛЯ ОЦЕНКИ ЭФФЕКТИВНОСТИ РЕМИНЕРАЛИЗАЦИИ ТВЁРДЫХ ТКАНЕЙ ЗУБА</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Alexandrov</surname><given-names>Mikhail Timofeevich</given-names></name><name xml:lang="ru"><surname>Александров</surname><given-names>Михаил Тимофеевич</given-names></name></name-alternatives><bio xml:lang="en"><p>Dr.med. Sci.,Professor</p></bio><bio xml:lang="ru"><p>д-р мед. наук. профессор</p></bio><email>alex_mta@mail.ru</email><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Polyakova</surname><given-names>M. A</given-names></name><name xml:lang="ru"><surname>Полякова</surname><given-names>М. А</given-names></name></name-alternatives><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Kukushkin</surname><given-names>V. I</given-names></name><name xml:lang="ru"><surname>Кукушкин</surname><given-names>В. И</given-names></name></name-alternatives><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Bagramova</surname><given-names>G. E</given-names></name><name xml:lang="ru"><surname>Баграмова</surname><given-names>Г. Э</given-names></name></name-alternatives><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Babina</surname><given-names>K. S</given-names></name><name xml:lang="ru"><surname>Бабина</surname><given-names>К. С</given-names></name></name-alternatives><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib><contrib contrib-type="author"><name-alternatives><name xml:lang="en"><surname>Dmitrieva</surname><given-names>E. F</given-names></name><name xml:lang="ru"><surname>Дмитриева</surname><given-names>Е. Ф</given-names></name></name-alternatives><xref ref-type="aff" rid="aff1"/><xref ref-type="aff" rid="aff2"/></contrib></contrib-group><aff-alternatives id="aff1"><aff><institution xml:lang="en">Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation</institution></aff><aff><institution xml:lang="ru">Федеральное государственное автономное образовательное учреждение высшего образования «Первый Московский государственный медицинский университет им. И.М. Сеченова» Министерства здравоохранения Российской Федерации (Сеченовский университет)</institution></aff></aff-alternatives><aff-alternatives id="aff2"><aff><institution xml:lang="en">Federal State budget Educational Institution of Higher Education South Ural State Medical University of the Ministry of Health of the Russian Federation</institution></aff><aff><institution xml:lang="ru">Федеральное государственное бюджетное образовательное учреждение высшего образования «Южно-Уральский государственный медицинский университет» Министерства здравоохранения Российской Федерации</institution></aff></aff-alternatives><pub-date date-type="pub" iso-8601-date="2018-10-15" publication-format="electronic"><day>15</day><month>10</month><year>2018</year></pub-date><volume>22</volume><issue>5</issue><issue-title xml:lang="en">VOL 22, NO5 (2018)</issue-title><issue-title xml:lang="ru">ТОМ 22, №5 (2018)</issue-title><fpage>220</fpage><lpage>223</lpage><history><date date-type="received" iso-8601-date="2020-08-04"><day>04</day><month>08</month><year>2020</year></date></history><permissions><copyright-statement xml:lang="en">Copyright ©; 2018, Eco-Vector</copyright-statement><copyright-statement xml:lang="ru">Copyright ©; 2018, ООО "Эко-Вектор"</copyright-statement><copyright-year>2018</copyright-year><copyright-holder xml:lang="en">Eco-Vector</copyright-holder><copyright-holder xml:lang="ru">ООО "Эко-Вектор"</copyright-holder><ali:free_to_read xmlns:ali="http://www.niso.org/schemas/ali/1.0/"/></permissions><self-uri xlink:href="https://rjdentistry.com/1728-2802/article/view/42188">https://rjdentistry.com/1728-2802/article/view/42188</self-uri><abstract xml:lang="en"><p>The purpose of the study-to justify the effectiveness of the method of Raman-fluorescence diagnostics in the assessment of the remineralisation of the hard tissues of the tooth. In preclinical in vitro study on the model 25 the test object teeth (the incisors of the lower jaw) removed as clinically indicated, carried out Raman-fluorescence spectroscopy with a wavelength of probe radiation of 532 nm. The advantages of Raman-fluorescence spectroscopy are expressiveness, noninvasiveness, simple and non-destructive control of the degree of remineralization of hard tooth tissues [1-3]. In the course of the study, a qualitative and quantitative analysis of the content and distribution of hydroxyapatite in the enamel in the normal and with the use of remineralizing drugs was carried out. The high sensitivity and reproducibility of the method allowed us to assess the degree of mineralization of the tooth, the effectiveness of remineralizing drugs.</p></abstract><trans-abstract xml:lang="ru"><p>Цель исследования - обосновать эффективность метода раман-флюоресцентной диагностики в оценке реминерализации твёрдых тканей зуба. В доклиническом исследовании in vitro на 25 модельных тест-объектах зубов (резцы нижней челюсти), удалённых по клиническим показаниям, проводили раман-флюоресцентную спектроскопию с длиной волны зондирующего излучения 532 нм. Преимуществами раман-флюоресцентной спектроскопии являются экспрессность, неинвазивность, простой и неразрушающий контроль степени реминерализации твёрдых тканей зуба [1-3]. В процессе исследования проведён качественный и количественный анализ содержания и распределения гидроксиапатита в эмали в норме и при использовании реминерализующих препаратов. Высокая чувствительность и воспроизводимость метода позволили нам оценивать степень минерализации зуба, эффективность реминерализующих препаратов.</p></trans-abstract><kwd-group xml:lang="en"><kwd>enamel</kwd><kwd>remineralization</kwd><kwd>hydroxyapatite</kwd><kwd>combination fluorescence spectroscopy</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>эмаль</kwd><kwd>реминерализация</kwd><kwd>гидроксиапатит</kwd><kwd>раман-флюоресцентная спектроскопия</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Movasaghi Z., Rehman S., Rehman I.U. Fourier transform infrared (FTIR) spec- troscopy of biological tissues. Appl. Spectros. Rev.2008; 43: 134-79.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Boskey A.L., Mendelsohn R. Infrared spectroscopic characterization of mineralized tissues. Vib. Spectros. 2005; 38: 107-14.</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Krafft C., Sergo V. 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