Oral microecosystem in asthma

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Abstract

Asthma-induced changes in the oral cavity may lead to microbial contamination, increasing the risk of dental caries, periodontal disease, and candidiasis.

This literature review examines the most relevant microorganism-associated oral diseases in asthma patients, as well as the mechanisms of their development.

The literature search and analysis were performed using international databases Google Scholar, Scopus, PubMed, Web of Science, disserCat, and eLIBRARY.RU for the period between 2004 and 2024. The following search terms were used: oral cavity, bronchial asthma, and microbes.

A total of 267 publications were identified, of which 22 were deemed relevant. Dental diseases associated with changes in the oral microecosystem (such as dental caries, gingivitis, periodontal disease, and candidiasis) and the mechanisms of their development were described based on the literature data for asthma patients. The study found that these disorders can be caused by autoimmune processes and other factors that alter oral homeostasis and activate pathogens in the oral cavity.

It was shown that changes in oral microbiota caused by microecosystem alterations contribute to the development of dental diseases, affecting both oral and general health.

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About the authors

Natalia A. Latysh

Peoples’ Friendship University of Russia

Author for correspondence.
Email: dr.latysh1978@mail.ru
ORCID iD: 0009-0001-0631-9819
Russian Federation, Moscow

Svetlana N. Razumova

Peoples’ Friendship University of Russia

Email: razumova_sv@mail.ru
ORCID iD: 0000-0002-9533-9204
SPIN-code: 6771-8507

MD, Dr. Sci. (Medicine), Professor

Russian Federation, Moscow

Nikolay V. Sturov

Peoples’ Friendship University of Russia

Email: sturov-nv@rudn.ru
ORCID iD: 0000-0002-3138-8410
SPIN-code: 2805-9823

Cand. Sci. (Medicine), Associate Professor

Russian Federation, Moscow

Anzhela S. Brago

Peoples’ Friendship University of Russia

Email: anzhela_bogdan@mail.ru
ORCID iD: 0000-0001-8947-4357
SPIN-code: 2437-8867

MD, Cand. Sci. (Medicine), Associate Professor

Russian Federation, Moscow

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СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
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