Factor analysis for assessing the etiopathogenesis of facial boils in military personnel

封面


如何引用文章

全文:

开放存取 开放存取
受限制的访问 ##reader.subscriptionAccessGranted##
受限制的访问 订阅或者付费存取

详细

Background: Boils are the most prevalent non-odontogenic inflammatory condition of the head and neck. The treatment of skin and subcutaneous tissue inflammations in the Russian Armed Forces (RAF) is a pressing issue. We were unable to find any data on the etiopathogenesis of facial boils in otherwise healthy RAF members, as well as the factors that contribute to the development of this condition.

Aim: To examine the causes of facial boils in military personnel, the factors that contribute to their development, and the association between them using factor analysis.

Materials and Methods: Between 2019 and 2021, 53 patients aged 18 to 25 years were examined and treated for abscess-forming face boils. Of these, 38 (72%) were conscripts and 15 (28%) were contract servicemen. At admission, clinical examinations (complaints, history taking, status localis, facial skin type and status) and laboratory tests (complete blood count, blood chemistry, immunoassay, and bacterial tests, including the composition and antibiotic sensitivity of microflora) were performed. The control group included 30 otherwise healthy individuals aged 18 to 25 years. A mathematical model for predicting maxillofacial boil development in military personnel was generated using binomial regression analysis (logistic regression). The following variables were considered: age, length of service, season of disease development, serum glucose level, lymphocyte count, white blood cell count, CD3+, CD4+, CD8+, IgA, IgG, IgM, immunosuppressive regulatory T cells (CD4+CD25brightCD45+; % of all T helper cells), skin type, and microbial composition of maxillofacial skin.

Results: The mathematical model revealed that oily skin in combination with specific blood lymphocyte (20.30±1.03%) and IgG parameters (10.15±0.70%) increases the risk of maxillofacial boils in military personnel.

Conclusion: The study revealed the cumulative effect of general and local factors on the development and progression of facial boils in military personnel, allowing for more accurate prevention and treatment strategies.

全文:

受限制的访问

作者简介

Irina Borodulina

Kirov Military Medical Academy

Email: borodulina59@mail.ru
ORCID iD: 0000-0003-1036-6455
SPIN 代码: 3067-6777

MD, Dr. Sci (Medicine), Professor

俄罗斯联邦, St. Petersburg

Tatiana Petrova

Kirov Military Medical Academy

编辑信件的主要联系方式.
Email: tanya-petrova-1995@yandex.ru
ORCID iD: 0000-0001-9079-1149
SPIN 代码: 1406-9138

MD, Cand. Sci. (Medicine)

PHD, lecturer at the Department of Maxillofacial Surgery and Surgical Dentistry of the V.Med. CM. Kirov
俄罗斯联邦, St. Petersburg

Valentin Chernegov

Kirov Military Medical Academy

Email: vchernegov@mail.ru
ORCID iD: 0000-0001-9191-4016
SPIN 代码: 9301-4984

MD, Cand. Sci. (Medicine), Associate Professor

俄罗斯联邦, St. Petersburg

参考

  1. Kulakov AA, Braylovskaya TB, Grebnev GA, et al. Comparative characteristics of the incidence of boils in the maxillofacial area in military personnel and civilians. Dentistry. 2022;101(3):31–37. doi: 10.17116/stomat202210103131
  2. Imbryakov KV, Nikolsky VYu. Comparison of morbidity and treatment tactics for patients with boils and facial carbuncles in the Samara and Kirov regions. Russian Journal of Dentistry. 2013;5:27–29. EDN: RVOYKX
  3. Solovyov MM, Bolshakov OP, Galetsky DV. Purulent-inflammatory diseases of the head and neck: etiology, pathogenesis, clinical picture, treatment. Moscow: Smart Doctor; 2016. 192 p. (In Russ.)
  4. Fayzullina GA, Mirsaeva FZ. Etiopathogenetic features of a boil in the maxillofacial region. Medical Bulletin of the North Caucasus. 2018;11(13):38–41. doi: 10.14300/mnnc.2018.13011
  5. Petrova TV, Borodulina II, Grebnev GA, et al. Analysis of the incidence of facial boils in military personnel. News of the Russian Military Medical Academy. 2021;40:121–124. EDN: ZVHTGQ
  6. Evdokimov VI, Sivaschenko PP, Grigoriev SG. Morbidity rates for contract servicemen of the Armed Forces of the Russian Federation (2013–2016). St. Petersburg: Polytechnics-print; 2018. 80 p. (In Russ.) EDN: TUXSHB
  7. Grigoriev SG, Evdokimov VI, Ivanov VV, et al. Medical and statistical characteristics of the incidence of conscripted military personnel of the Armed Forces of the Russian Federation (2007–2016). Military Medical Journal. 2017;10(338):4–14. (In Russ.) EDN: VZNYJN
  8. Noble WC. Skin bacteriology and the role of Staphylococcus aureus in infection. Br J Dermatol. 1998;139(53):9–12. doi: 10.1046/j.1365-2133.1998.1390s3009.x
  9. Artiz O, Sinai M, Solomon M, Schwartz E. Recurrent furunculosis in returning travelers: newly defined entity. J Trav Med. 2015;22(1):21–25. doi: 10.1111/jtm.12151
  10. Petrova TV, Borodulina II, Tegza NV. Etiopathogenetic aspects of boils in the maxillofacial region (literature review). Modern Science: current issues of theory and practice. Series: natural and technical sciences. 2021;12:209–216. doi: 10.37882/2223-2966.2021.12.25
  11. Ibler KS, Kromann CB. Recurrent furunculosis — challenges and management: a review. Clin Cosmet Investig Dermatol. 2014;7:59–64. doi: 10.2147/CCID.S35302
  12. Fleryanovich MS, Pokhodenko-Chudakova IO. Lipid spectrum of patients with boils of the maxillofacial area at the present stage. Medical Journal. 2019;2:124–128. EDN: NHWOAX
  13. Kalinina NM. Immunity disorders in recurrent furunculosis. Cytokines and Inflammation. 2003;2(3):41–44. EDN: HRRJRR
  14. Kasenova NS. Etiopathogenesis and frequency of development of boils and carbuncles of the maxillofacial region: (literature review). Healthcare of Kyrgyzstan. 2018;11(13):38–41. EDN: ZVLCUF
  15. Vyazitsky PO, Dyakonov MM, Endaltsev BV. Adaptation of a young soldier to the conditions of military service and prevention of maladaptive disorders. Moscow: USSR Ministry of Defense; 1990. 28 p.
  16. Paklin RV. Indicators of adaptation of conscript soldiers to new living conditions. Perm Medical Journal. 2010;27(1):113–117. EDN: NCKMUH

补充文件

附件文件
动作
1. JATS XML
下载
2. Fig. 1. A graph of the intersection of true positive and true negative values. If the threshold value (p) is greater than 0.565 (dotted line), then the patient has a high risk of developing a boil.

下载 (68KB)
索引源数据
3. Fig. 2. ROC-curve of the ratio of diagnostic sensitivity and specificity in determining the risk of developing a facial furuncle, type of facial skin, the content of lymphocytes and IgG in the blood. The area under the red line shows the number of correct results (95%).

下载 (65KB)
索引源数据

版权所有 © Eco-Vector, 2024


СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
Регистрационный номер и дата принятия решения о регистрации СМИ: серия ПИ № ФС 77 - 86295 от 11.12.2023 г. 
СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
Регистрационный номер и дата принятия решения о регистрации СМИ: серия ЭЛ № ФС 77 - 80635 от 15.03.2021 г.