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Features of pain sensitivity during premedication with xenon in patients before outpatient dental interventions
- Authors: Shugailov I.A.1, Moskovets O.N.2, Sergeeva J.I.1, Drobyshev A.Y.2, Chausskaja I.Y.2
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Affiliations:
- Academy of Innovative Stomatology
- Russian University of Medicine
- Issue: Vol 28, No 1 (2024)
- Pages: 21-28
- Section: Clinical Investigation
- Submitted: 17.10.2023
- Accepted: 05.05.2024
- Published: 10.06.2024
- URL: https://rjdentistry.com/1728-2802/article/view/323125
- DOI: https://doi.org/10.17816/dent323125
- ID: 323125
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Abstract
BACKGROUND: Premedication in outpatient dental interventions normalizes pain sensitivity and emotional state of patients. Inhalation of xenon-oxygen mixture can be an effective means for it.
AIM: To study the effect of xenon premedication on pain sensitivity in patients with outpatient dental interventions.
MATERIALS AND METHODS: Twenty patients were studied. Emotional and personal characteristics of patients were determined using the Eysenck test, Spielberger–Khanin personal anxiety scale, and hospital scale of anxiety and depression. Pain sensitivity was assessed using pain thresholds and somatosensory evoked potentials of the brain before and after inhalation of xenon-oxygen mixture at a concentration of 30/70 for 3 minutes.
RESULTS: According to the results of psychological testing, all examined patients were characterized by a stable psychological sphere and predominantly lowered anxiety and constituted a group with insignificantly different emotional and personal characteristics. Before inhalation, pain sensitivity in patients varied significantly. After inhalation, multidirectional changes in pain sensitivity occurred, which were expressed in a decrease and an increase in pain sensitivity thresholds and the degree of activation of brain structures.
CONCLUSION: Preoperative stress can both exacerbate and reduce pain sensitivity in patients. The use of inhalation of a xenon-oxygen mixture at a concentration of 30/70 for 3 minutes as a premedication causes multidirectional changes in the sensitivity of tissues and organs in the maxillofacial region in patients before outpatient dental interventions, which may be caused by a change in the activity of endogenous antinociceptive (analgesic) system.
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About the authors
Igor A. Shugailov
Academy of Innovative Stomatology
Email: 9978753@mail.ru
ORCID iD: 0000-0001-5304-6078
SPIN-code: 5681-7569
Russian Federation, Москва
Oleg N. Moskovets
Russian University of Medicine
Author for correspondence.
Email: moskovets.oleg@yandex.ru
ORCID iD: 0000-0001-9686-1769
SPIN-code: 8110-8715
Russian Federation, Moscow
Julia I. Sergeeva
Academy of Innovative Stomatology
Email: 0196268@gmail.com
ORCID iD: 0000-0002-2703-1056
SPIN-code: 4515-2220
Russian Federation, Moscow
Alexey Y. Drobyshev
Russian University of Medicine
Email: dr.drobyshev@gmail.com
ORCID iD: 0000-0002-1710-6923
SPIN-code: 6683-8226
Russian Federation, Moscow
Irina Y. Chausskaja
Russian University of Medicine
Email: dr.chausskaya@mail.ru
ORCID iD: 0000-0001-9674-1919
SPIN-code: 2957-4091
Russian Federation, Moscow
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