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Comparative analysis of oral fluid metabolism parameters between patients with complicated and uncomplicated implantation
- Authors: Tlustenko V.S.1, Koshelev V.A.1, Tlustenko V.P.1, Ivashenko A.V.1
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Affiliations:
- Samara State Medical University
- Issue: Vol 28, No 1 (2024)
- Pages: 53-60
- Section: Clinical Investigation
- Submitted: 16.01.2024
- Accepted: 04.02.2024
- Published: 10.06.2024
- URL: https://rjdentistry.com/1728-2802/article/view/625678
- DOI: https://doi.org/10.17816/dent625678
- ID: 625678
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Abstract
ВACKGROUND: Modern scientific research continues to develop promising areas for diagnosing inflammatory complications after dental implantation. Analysis of studies shows that inflammatory complications depend on various factors, the establishment of which can be challenging. Hence, saliva diagnostics opens up broad prospects for studying the pathogenetic basis of the development of inflammatory processes.
АIM: To study in a comparative aspect the metabolic status of complicated and uncomplicated implantation.
MATERIALS AND METHODS: This study examined 88 patients (30 with peri-implant mucositis [main group I], 28 with uncomplicated implantation [comparison group II], and 30 controls [control group]) aged 45.3±2.4 years who were followed up for 1–3 years.
RESULTS: Based on the results of the studies and comparative analysis of complicated and uncomplicated implantation, previously unknown data on their distinctive metabolic characteristics were obtained and presented. With complicated implantation, these include a characteristic increase in C-reactive protein, iron, and uric acid and a decrease in calcium levels.
CONCLUSION: New information revealing prognostically significant factors of gastric cancer metabolism during complicated and uncomplicated implantation has been obtained. The identified changes in metabolism during implantation should be considered and differentiated from early metabolic signs of inflammation. The study of oral fluid is objective and promising in the diagnosis of the inflammatory process and its prognosis.
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About the authors
Vladimir S. Tlustenko
Samara State Medical University
Email: vlastt@yandex.ru
ORCID iD: 0000-0002-7429-9135
SPIN-code: 8537-5155
MD, Cand. Sci. (Medicine), Associate Professor
Russian Federation, SamaraVladimir A. Koshelev
Samara State Medical University
Author for correspondence.
Email: stomvk@yandex.ru
ORCID iD: 0000-0001-8479-0342
SPIN-code: 6886-6628
Russian Federation, Samara
Valentina P. Tlustenko
Samara State Medical University
Email: stas-763@yandex.ru
ORCID iD: 0000-0002-2756-5277
SPIN-code: 2737-9657
MD, Dr. Sci. (Medicine), Professor
Russian Federation, SamaraAlexandr V. Ivashenko
Samara State Medical University
Email: a.v.ivaschenko@samsmu.ru
ORCID iD: 0000-0002-2965-963X
SPIN-code: 5066-8179
MD, Dr. Sci. (Medicine), Professor
Russian Federation, SamaraReferences
- Bronshteyn DA, Olesov EE, Zaslavsky RS, et al. Results of orthopedic rehabilitation of patients full absence of teeth depending on the design of prosthesis on dental implants. Russian Bulletin of Dental Implantology. 2017;(2):45–49. EDN: KKGUKW
- Ashurov GG, Mullodzanov GE, Ismoilov AA. Results determination of the needs patients with disadvantage somatic background in dental implantation methods. Russian Bulletin of Dental Implantology. 2017;(2):60–63. EDN: QHYDIU
- Kulakov АА, Gvetadze RSh, Brailovskaya TV, et al. Modern approaches to dental implants placement in deficient alveolar bone. Stomatology. 2017;96(1):43–45. EDN: YGDILR doi: 10.17116/stomat201796143-45
- Melnichenko DI, Romanenko IG, Melnichenko PV. Implant-supported dentures. Vestnik medicinskogo instituta “REAVIZ”: reabilitacija, vrach i zdorov’e. 2019;(6):178–187. EDN: RGJVDJ
- Alassy H, Parachuru P, Wolff L. Peri-implantitis diagnosis and prognosis using biomarkers in peri-implant crevicular fluid: a narrative review. Diagnostics (Basel). 2019;9(4):214. doi: 10.3390/diagnostics9040214
- Monje A, Caballé-Serrano J, Nart J, et al. Diagnostic accuracy of clinical parameters to monitor peri-implant conditions: a matched case-control study. J Periodontol. 2018;89(4):407–417. doi: 10.1002/JPER.17-0454
- Rito-Macedo F, Barroso-Oliveira M, Paranhos LR, et al. Implant insertion angle and depth: peri-implant bone stress analysis by the finite element method. J Clin Exp Dent. 2021;13(12):e1167–e1173. doi: 10.4317/jced.58930
- Alenazi A. Association between rheumatoid factors and proinflammatory biomarkers with implant health in rheumatoid arthritis patients with dental implants. Eur Rev Med Pharmacol Sci. 2021;25(22):7014–7021. doi: 10.26355/eurrev_202111_27251
- Astolfi V, Ríos-Carrasco B, Gil-Mur FJ, et al. Incidence of peri-implantitis and relationship with different conditions: a retrospective study. Int J Environ Res Public Health. 2022;19(7):4147. doi: 10.3390/ijerph19074147
- Mitronin AV, Antonova OA. Biomarkers of mixed saliva as indicators of body condition. Russian Journal of Stomatology. 2022;(15):1:61–62. (In Russ). EDN: WVMZVG doi: 10.17116/rosstomat20221501125
- Kuzmina DA, Voroncov PV. Biochemical methods of assessment of bone metabolism. Markers and their clinical value. Medicine: Theory and Practice. 2018;3(S):99–106. EDN: YPUSCT
- Krebs M, Kesar N, Begić A, et al. Incidence and prevalence of peri-implantitis and peri-implant mucositis 17 to 23 (18.9) years postimplant placement. Clin Implant Dent Relat Res. 2019;21(6):1116–1123. doi: 10.1111/cid.12848
- Mikayelyan NP, Komarov OS, Davydov VV, Meisner IS. Biochemistry of oral fluid in the norm and pathology: textbook. Moscow: IKAR. 2017. 64 p. (In Russ).
- Alemayehu DB, Jeng YR. Three-dimensional finite element investigation into effects of implant thread design and loading rate on stress distribution in dental implants and anisotropic bone. Materials (Basel). 2021;14(22):6974. doi: 10.3390/ma14226974
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