Current prevalence and etiologic factors of oral galvanism

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Abstract

This review analyzed specialized articles published over the past 25 years, covering data on the prevalence and etiologic factors of oral galvanism. The relationships between these factors and the frequency of clinical manifestations associated with galvanism were evaluated. A descriptive method was applied for this analysis.

According to the reviewed scientific sources, corrosion of metal-based dental prostheses and restorations and systemic diseases may be considered mutually exacerbating pathological processes in the presence of electrochemical reactions in the oral cavity. However, this association currently lacks objective confirmation.

Despite existing evidence highlighting the significant role of oral fluids in galvanism development and their impact on oral tissues and organs, no clear criteria have been established for employing physicochemical, biochemical, or immunologic indicators for the diagnostic and prognostic monitoring of galvanism.

Taken together, these findings highlight the lack of an established framework for predicting and diagnosing oral galvanism. Consequently, unresolved questions and directions for future research are outlined.

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About the authors

Irina O. Pohodenko-Chudakova

Belarusian State Medical University

Author for correspondence.
Email: ip-c@yandex.ru
ORCID iD: 0000-0002-0353-0125
SPIN-code: 9486-9067

MD, Dr. Sci. (Medicine), Professor

Belarus, Post Box 1, 9 Kosmonavtov st, Minsk, 220025

Volha S. Fralova

Belarusian State Medical University

Email: fos91@mail.ru
ORCID iD: 0000-0001-9868-2510
SPIN-code: 1884-2694
Belarus, Post Box 1, 9 Kosmonavtov st, Minsk, 220025

References

  1. Krikheli NI, Ivankova MV. The application of laminars in aesthetic stomatology. Russian Journal of Stomatology. 2014;7(3):8–11. EDN: TANNTF
  2. Sultanov AA, Pervov YuYu, Yatsenko AK. Physical and chemical properties of implants, their interaction with surrounding tissues and environments of the oral cavity (literature review). Medical Newsletter of Vyatka. 2019;(2):80–86. (In Russ.) EDN: WRSCOO
  3. Shulyatnikova O, Rogozhnikov G, Porozova S, et al. Ffunctional nanostructured materials based on titanium dioxide for use in orthopedic dentistry. Actual Problems in Dentistry. 2020;16(1):171–177. doi: 10.18481/2077-7566-20-16-1-171-177 EDN: EUISKW
  4. Borisova E, Komova A, Verbitsky E, Idris AYa. Galvanosis of the oral cavity. Actual Problems in Dentistry. 2019;15(1):5–9. doi: 10.18481/2077-7566-2018-15-1-5-9 EDN: LDJLYX
  5. Sarkisyan N, Zaraev P, Khlystova K, Yuffa E. Early diagnosis of galvanosis in the oral cavity. Vrach. 2020;31(6):76–78. doi: 10.29296/25877305-2020-06-15 EDN: WTRYDB
  6. Lianides IM, Mikhaylova MV. Galvanism. Causes and complications. Modern Scientific Researches and Innovations. 2016;(11):911–914. EDN: XRNOST
  7. Matveeva EV, Antonova IN, Kipchuk AV. The effect of comorbidities on periodontal and hygiene indices, and oral fluid mineral composition. Parodontologiya. 2023;28(1):67–74. doi: 10.33925/1683-3759-2023-28-1-67-74 EDN: XHJTGT
  8. Paszynska E, Tyszkiewicz-Nwafor M, Slopien A, et al. Study of salivary and serum vaspin and total antioxidants in anorexia nervosa. Clin Oral Investig. 2018;22(8):2837–2845. doi: 10.1007/s00784-018-2370-9 EDN: QKROEM
  9. Karton E, Dzgoeva F, Shestakova M, et al. Investigation of the level of monosaccharides in saliva of patients with impaired carbohydrate metabolism. Georgian Med News. 2023;(338):14–18.
  10. Sabantseva EG, Ivanova EV, Rabinovich IM. Manifestations of allergic reactions occurring at a dental appointment. Stomatologiia (Mosk). 2021;100(6-2):29–32. doi: 10.17116/stomat202110006229 EDN: EXYCRZ
  11. Fletcher R, Harrison W, Crighton A. Dental material allergies and oral soft tissue reactions. Br Dent J. 2022;232(9):620–625. doi: 10.1038/s41415-022-4195-9 EDN: OVGYVM
  12. Zholudev DS, Berdnikov RB, Grigoryev SS. Study of the toxic properties of naivotnyh new dental material based on oxide alumina. Actual Problems in Dentistry. 2014;10(5):37–40. doi: 10.18481/2077-7566-2014-0-5-37-40
  13. Ge X, Ye Q, Song L, et al. Synthesis and evaluation of a novel co-initiator for dentin adhesives: polymerization kinetics and leachables study. JOM (1989). 2015;67(4):796–803. doi: 10.1007/s11837-015-1335-6 EDN: GQFZHH
  14. Pohodenko-Chudakova IO, Maksimovich EV. Toxic reactions in dentistry and their prevention. Minsk: Izd. Center BSU; 2017. (In Russ.)
  15. De Angelis F, Sarteur N, Buonvivere M, et al. Meta-analytical analysis on components released from resin-based dental materials. Clin Oral Investig. 2022;26(10):6015–6041. doi: 10.1007/s00784-022-04625-4 EDN: KUTOSG
  16. Sarkisjan NG, Zaraev PI, Hlystova KA, Juffa EP. Determination of the galvanic state of the oral cavity in the presence of metallic inclusions. Stomatologiya. 2020;(2):66–70. (In Russ.) EDN: FEIPOJ
  17. Danilina TF, Zhidovinov AV. Galvanosis as a causative factor in development of precancerous lesions of oral mucosa. Volgograd Journal of Medical Research. 2012;(3):37–39. EDN: THIWFN
  18. Bajdik OD, Filjurin MD, Sysoljatin PG, Titarenko MS. Precancerous diseases of the oral mucosa and the red border of the lips. Tomsk: SibGMU Publishing House; 2018. (In Russ.)
  19. Stuetz H, Reihs EI, Neuhaus W, et al. The cultivation modality and barrier maturity modulate the toxicity of industrial zinc oxide and titanium dioxide nanoparticles on nasal, buccal, bronchial, and alveolar mucosa cell-derived barrier models. Int J Mol Sci. 2023;24(6):5634. doi: 10.3390/ijms24065634 EDN: RUDMXP
  20. Garhammer P, Schmalz G, Hiller KA, et al. Patients with local adverse effects from dental alloys: frequency, complaints, symptoms, allergy. Clin Oral Investig. 2001;5(4):240–249. doi: 10.1007/s007840100127 EDN: ASRWGV
  21. Lygre GB, Gjerdet NR, Grønningsaeter AG, Björkman L. Reporting on adverse reactions to dental materials — intraoral observations at a clinical follow-up. Community Dent Oral Epidemiol. 2003;31(3):200–206. doi: 10.1034/j.1600-0528.2003.00037.x
  22. Borisova EG, Nikitenko VV, Khlebnikov DA. Methods of differential diagnosis galvanosis and glossodinii on an outpatient basis. The Journal of Scientific Articles Health and Education Millennium. 2016;18(4):29–31. EDN: WGXIBT
  23. Pursanova AE, Kazarina LN, Belozerov AE, et al. Improvement of diagnostics and treatment of pre-malignant condition of the oral mucosa. Medical Newsletter of Vyatka. 2019;(2):46–50. (In Russ.) EDN: DACWZX
  24. Shlyk KS, Bredikhina AA, Grimanov NV. Features of galvanosis in dental practice. Colloquium Journal. 2019;39(15-3):62–63. doi: 10.24411/2520-6990-2019-10469
  25. Borisova EG, Komova AA. Diagnostics of galvanosis in outpatient conditions. The Journal of Scientific Articles Health and Education Millennium. 2018;20(4):39–41. doi: 10.26787/nydha-2226-7425-2018-20-4-38-41 EDN: YXIEJW
  26. Vasil’ev MA, Makeeva IN, Gurin PA. Electrochemical corrosion of dental alloys. Prog Phys Met. 2019;20(2):310–346. (In Russ.)
  27. Manin OI, Dubova LV, Romodanovsky PO, et al. Comparative evalution of the electrochemical potentials difference indicators of dental alloys obtained by a new domestic device. Parodontologiya. 2023;28(3):257–263. doi: 10.33925/1683-3759-2023-800 EDN: DZCABM
  28. Breshhenko EE, Bykov IM. Biochemistry of the oral cavity, oral and gingival fluids. Krasnodar: Kuban State Medical University; 2018. (In Russ.)
  29. Makeeva IM, Volkov AG, Dikopova NZh, Makarenko NV. The determination of electrochemical potentials in the oral cavity, as a way to diagnose galvanic syndrome, which contributes to the development of diseases of the mucous membrane. Head and Neck. 2018;(1):42–45. doi: 10.25792/HN.2018.6.1.42-45 EDN: SNFGTK
  30. Utyuzh AS, Yumashev AV, Zagorskij VV, et al. Clinical aspects of biomechanics for implants joined in unit. Sovremennaya nauka: aktual’nye problemy teorii i praktiki. Seriya: estestvennye i tekhnicheskie nauki. 2016;(7):92–97. EDN: WYRJQL
  31. Mikhalchenko DV, Zhidovinov AV, Denisenko LN, et al. Corrosion of metals in the oral cavity, as a factor of galvanosis. Modern Problems of Science and Education. 2015;(3):43. EDN: TYSHBP
  32. Mikulewicz M, Chojnacka K, Woźniak B, Downarowicz P. Release of metal ions from orthodontic appliances: an in vitro study. Biol Trace Elem Res. 2012;146(2):272–280. doi: 10.1007/s12011-011-9233-4 EDN: DMVXMS
  33. Chantarawaratit PO, Yanisarapan T. Exposure to the oral environment enhances the corrosion of metal orthodontic appliances caused by fluoride-containing products: Cytotoxicity, metal ion release, and surface roughness. Am J Orthod Dentofacial Orthop. 2021;160(1):101–112. doi: 10.1016/j.ajodo.2020.03.035 EDN: MFEGSQ
  34. Patil Sh, Muruganandhan Ja, Felicita AS, et al. Effect of fluoridated mouthwashes on corrosion property of orthodontic appliances: a narrative review. Journal of Contemporary Dental Practice. 2022;23(4):460–466. doi: 10.5005/jp-journals-10024-3326 EDN: LFPDFO
  35. Ovcharenko YeN, Zhadko SI, Kolbasin PN, Nikolskaya VA. The effect of allgations of orthopaedic constructions on the processes of free radical oxidation in the oral liquid. Journal of the Grodno State Medical University. 2014;(3):45–48. EDN: SQIWEV
  36. Timofeev AA. Role of galvanic factor in the occurrence of malignant tumours of oral tissues. Sovremennaja stomatologija. 2005;(4):120–123. (In Russ.)
  37. Mamytova AB, Aidarbekova AA, Turgunbaev UA, Kasenova NS. Oncostomatology, radiation therapy and chemotherapy. Bishkek: KRSU; 2017. (In Russ.)
  38. Timofeev AA, Ushko NA, Timofeev AA, et al. Galvanism as one of development factors of oral mucosa malignant neoplasms. Sovremennaja stomatologija. 2011;(2):103–111. (In Russ.).
  39. Volkov AG, Dikopova NZh, Amanatidi GE, et al. The results of the frequency of detection of galvanic couple of metal structures in of the oral mucosal diseases. Medical Alphabet. 2022;(7):27–30. doi: 10.33667/2078-5631-2022-7-27-30 EDN: ODNLIS
  40. Kudina AV, Sokorov IO. Corrosion — biotechnical system for destruction of technical objects reducing their quality and reliability. Science and Technioque. 2020;19(6):512–520. doi: 10.21122/2227-1031-2020-19-6-512-520 EDN: JIMXIF
  41. Efimova EV, Leonova LA, Bojcova EL. Studying the behavior of Ti-O-N coatings of coronary stents in tissue fluids. In: Chemistry and Chemical Technology in the XXI century: Proceedings of the XVIII International Scientific and Practical Conference of Students and Young Scientists named by Prof. L.P. Kulev (29.05–01.06.2017). Tomsk: NITPU; 2017. P. 360–361. (In Russ.) EDN: PRHECM
  42. Pohodenko-Chudakova IO, Kuznetsov YA, Ali TAA. Study of the hydrogen index (pH) of the oral cavity and oral fluid in normal state and in dental diseases. Sovremennaya stomatologiya. 2021;(4):22–24. EDN: BMXKWM
  43. Uchida H, Ovitt CE. Novel impacts of saliva with regard to oral health. J Prosthet Dent. 2022;127(3):383–391. doi: 10.1016/j.prosdent.2021.05.009 EDN: ZRUVTH
  44. Grechishnikov NS. Methods of diagnosing galvanosis. Nauchnoe obozrenie. Medicinskie nauki. 2017;(4):7–11. EDN: YFVNZB
  45. Mikhaylova MV, Gorodentseva YaYu. Ph measurement in orthopedic dentistry. Clinical Dentistry (Russia). 2018;87(3):83–85. doi: 10.37988/1811-153X_2018_3_83 EDN: YAMEWT
  46. Pravdivtsev VA, Shashmurina VR, Kirllov SK, et al. Pathological processes initiated ceramic-metal denture. Russian Journal of Dentistry. 2013;(3):30–34. EDN: QJAWHZ
  47. Maiborodin IV, Shevela AA, Toder MS, Shevela AI. The features of interaction between dental implants and organism tissues and the modern methods of creation of antibacterial covering on implant surfaces. Russian Journal of Stomatology. 2017;10(4):32–41. doi: 10.17116/rosstomat201710432-40 EDN: YPXJMQ
  48. Nikitin SG, Petrov YuYu, Saleev RA, Amkhadova MA. Effect of physical and chemical factors, arising in elements of implantation systems, on central screws of heads at rehabilitation of patients in orthopedic dentistry clinic. Medical Alphabet. 2019;(4):35–39. doi: 10.33667/2078-5631-2019-4-34(409)-35-39 EDN: XVYTVE
  49. Kim KT, Eo MY, Nguyen TTH, Kim SM. General review of titanium toxicity. Int J Implant Dent. 2019;5(1):10. doi: 10.1186/s40729-019-0162-x EDN: VZRYLI
  50. Ragulin AV, Sereda AE, Olesov EE, et al. The content of trace elements in the oral fluid of users with non-removable prostheses on implants. Russian Bulletin of Dental Implantology. 2022;(1-2):72–77. EDN: JOEKIG
  51. Zholudev SE, Belokonova NA, Neustroeva TG. Clinical-experimental study of efficacy of tablets “corega tаbs for partial dentures” in individuals with arc dentures. Stomatologiia (Mosk). 2015;94(4):75–79. doi: 10.17116/stomat201594475-79 EDN: UGWJVB

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