Analysis of reparative osteogenesis in the augmentation zone using allogeneic lyophilized spongy bone tissue



如何引用文章

全文:

开放存取 开放存取
受限制的访问 ##reader.subscriptionAccessGranted##
受限制的访问 订阅或者付费存取

详细

BACKGROUND: The use of the implantation method in dental practice is constantly growing. The indications for its implementation are expanding, including in cases of significant atrophy of the alveolar process in order to restore bone volume using osteoplastic materials. The study of metabolic processes remains a pressing issue.

AIM: To evaluate reparative osteogenesis in the augmentation zone with allogeneic lyophilized cancellous bone tissue by analyzing metabolic criteria.

MATERIALS AND METHODS: The study included 41 people in the main group and 17 in the control group at the stage of osseointegration with an observation period of 1 to 12 weeks, the object of the study was oral fluid. Allogeneic lyophilized spongy bone tissue was used in the augmentation zone.

RESULTS: At 1–2 weeks, no statistically significant differences from the control values ​​were found. However, at 3–4 weeks, a slight increase in collagen C-telopeptide, osteocalcin, and a decrease in the activity of alkaline phosphatase and parathyroid hormone were noted. These changes indicate the development of the secondary remodeling stage by forming an osteoid matrix. After 12 weeks of observation, metabolic parameters are restored, indicating reparative osteogenesis.

CONCLUSION: The use of lyophilized spongy bone tissue ensures physiological osteogenesis.

全文:

受限制的访问

参考

  1. Kulakov АА, Gvetadze RSh, Brailovskaya TV, et al. Modern approaches to dental implants placement in deficient alveolar bone. Stomatologiia. 2017;96(1):43–45. (In Russ.) doi: 10.17116/stomat201796143-45. EDN YGDILR
  2. Popov N. Clinical aspects application of the individual reconstructive implant from the material lyophilized by allogennogo at the expressed atrophy of the bone tissue of jaws. The Actual problems in dentistry. 2018;14(2):86–92. (In Russ.) doi: 10.18481/2077-7566-2018-14-2-86-92. EDN XTXLRJ
  3. Avila-Ortiz G, Vegh D, Mukaddam K, et al. Treatment alternatives for the rehabilitation of the posterior edentulous maxilla. Periodontol 2000. 2023;93(1):183–204. doi: 10.1111/prd.12507
  4. Canullo L, Del Fabbro M, Colantonio F, et al. Sinus floor augmentation using crestal approach in conjunction with hydroxyapatite/cross-linked collagen sponge: A pilot study. Clin Implant Dent Relat Res. 2023;25(5):974–983. doi: 10.1111/cid.13236
  5. Dam VV, Trinh HA, Rokaya D, Trinh DH. Bone augmentation for implant placement: Recent advances. Int J Dent. 2022;8900940. doi: 10.1155/2022/8900940
  6. Chatzopoulos GS, Wolff LF. Dental implant failure and bone augmentation: A retrospective study. J Clin Exp Dent. 2023;15(3):e195-e204. doi: 10.4317/jced.60171
  7. Ghasemirad M, Chitsazi MT, Faramarzi M, et al. Histological examination of the effect of concentrated growth factor (CGF) on healing outcomes after maxillary sinus floor augmentation surgery. J Med Life. 2023;16(2):267–276. doi: 10.25122/jml-2021-0294
  8. Calciolari E, Corbella S, Gkranias N, et al. Efficacy of biomaterials for lateral bone augmentation performed with guided bone regeneration. A network meta-analysis. Periodontol 2000. 2023;93(1):77–106. doi: 10.1111/prd.12531
  9. Mateo GD, Mazón-Esteve JP, Pineda-Villacorta CR, et al. Frequency of surgical bone augmentation methods complementary to dental implant placement: A study evaluated with cone beam computed tomography. J Clin Exp Dent. 2023;15(12):e1029–e1034. doi: 10.4317/jced.61148
  10. Morgan N, Meeus J, Shujaat S, et al. CBCT for diagnostics, treatment planning and monitoring of sinus floor elevation procedures. Diagnostics (Basel). 2023;13(10):1684. doi: 10.3390/diagnostics13101684
  11. Gatin E, Nagy P, Iordache SM, et al. Preliminary assessment of in vivo Raman spectroscopy technique for bone quality evaluation of augmented maxillary sinus floor. Int J Environ Res Public Health. 2023;20(6):4789. doi: 10.3390/ijerph20064789
  12. Tavelli L, Barootchi S, Rodriguez MV, et al. Characterization of oral biomarkers during early healing at augmented dental implant sites. J Periodontal Res. 2025;60(3):206–214. doi: 10.1111/jre.13328
  13. Slesarev OV, Malchikova DV, Yunusova YR, et al. Influence of soft tissue on the reparative abilities of the jaw bone tissue in patients with dentoalveolar lesions. Russian Journal of Dentistry. 2023;27 (2):111–119. (In Russ.) doi: 10.17816/dent217214. EDN TFAQLS
  14. Lumbikananda S, Srithanyarat SS, Mattheos N, Osathanon T. Oral fluid biomarkers for peri-implantitis: A scoping review. Int Dent J. 2024;74(3):387–402. doi: 10.1016/j.identj.2023.11.005
  15. Mitronin AV, Antonova OA. Biomarkers of mixed saliva as indica-tors of body condition. Russian Journal of Stomatology. 2022;(15)1:61–62. (In Russ.) doi: 10.17116/rosstomat20221501125. EDN: WVMZVG.
  16. Fadli NA, Abdul Rahman M, Karsani SA, Ramli R. Oral and gingival crevicular fluid biomarkers for jawbone turnover diseases: A scoping review. Diagnostics (Basel). 2024;14(19):2184. doi: 10.3390/diagnostics14192184
  17. Tlustenko VP, Gil’miyarova FN, Golovina ES, et al. Preclinical diagnosis of dental periimplantitis. Russian Journal of Dentistry. 2011;2:28–29. (In Russ.) EDN: NWFCPH
  18. Kuzmina DA, Voroncov PV. Biochemical methods of assessment of bone metabolism. Markers and their clinical value. Medicine: Theory and Practice. 2018;3(S):99–106. (In Russ.) EDN: YPUSCT

补充文件

附件文件
动作
1. JATS XML
下载

版权所有 © Eco-Vector,


СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
Регистрационный номер и дата принятия решения о регистрации СМИ: серия ПИ № ФС 77 - 86295 от 11.12.2023 г. 
СМИ зарегистрировано Федеральной службой по надзору в сфере связи, информационных технологий и массовых коммуникаций (Роскомнадзор).
Регистрационный номер и дата принятия решения о регистрации СМИ: серия ЭЛ № ФС 77 - 80635 от 15.03.2021 г.