Fourier transform IR spectroscopic study of gamma-irradiated papain

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In papain macromolecules irradiated with γ-rays, fragments with terminal primary amino groups are formed, which appear in FTIR spectra as a broad peak with a maximum at 3440 cm–1, as well as an intense absorption band centred at 1706 cm–1 as a result of valence vibrations of carbonyl groups. The intensity of the absorption bands of the radiolysis products increases linearly with the irradiation dose of papain. At the same time, with increasing irradiation dose, a marked weakening of the intensity of the maxima of the absorption peaks of the peptide bond is observed, which indicates radiation destruction of the main chain of papain.

作者简介

S. Allayarov

Federal Research Center for Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences

编辑信件的主要联系方式.
Email: sadush@icp.ac.ru
俄罗斯联邦, Chernogolovka

T. Rudneva

Institute of microelectronics technology and high purity materials, Russian Academy of Sciences

Email: sadush@icp.ac.ru
俄罗斯联邦, Chernogolovka

S. Demidov

Federal Research Center for Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences

Email: sadush@icp.ac.ru
俄罗斯联邦, Chernogolovka

U. Allayarova

Federal Research Center for Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences

Email: sadush@icp.ac.ru
俄罗斯联邦, Chernogolovka

S. Chekalina

Federal Research Center for Problems of Chemical Physics and Medicinal Chemistry, Russian Academy of Sciences

Email: sadush@icp.ac.ru
俄罗斯联邦, Chernogolovka

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