Synthesis of a New Cobalt Complex with Catechol Dianion and Study of the Kinetics of its Redox-Activated Dissociation

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Resumo

A new redox-active cobalt(III) complex with a catechol dianion and two 4,4’-dimethoxy-2,2’-bipyridine ligands was synthesized. The reduction of the complex with ascorbic acid in an inert atmosphere was studied by NMR spectroscopy in situ. The reaction followed the first-order kinetics with respect to the starting complex, had a rate constant of 1.1 × 10−3 s−1, and was accompanied by the release of catechol, which served as a model drug.

Sobre autores

E. Khakina

Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences

Email: khakina90@ineos.ac.ru
Moscow, Russia

I. Nikovskii

Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences

Moscow, Russia

A. Danshina

Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences; Moscow Institute of Physics and Technology (National Research University)

Moscow, Russia; Dolgoprudnyi, Moscow oblast, Russia

E. Antoshkina

Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences; Moscow Institute of Physics and Technology (National Research University)

Moscow, Russia; Dolgoprudnyi, Moscow oblast, Russia

A. Rodionov

Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences

Moscow, Russia

Yu. Nelyubina

Nesmeyanov Institute of Organoelement Compounds, Russian Academy of Sciences

Moscow, Russia

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