Analyzing the efficacy of various treatment options for patients with oral mucosal hyperkeratosis

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Abstract

Diseases of the oral mucosa (COR), characterized by a violation of its cornea, constitute a vast group among the variety of diseases of COR, of particular interest is a separate group called — hyperkeratosis of the oral mucosa. Current treatment protocols include a variety of therapeutic and surgical methodologies and principles, with surgical excision of the lesion being the primary treatment measure. However, surgical treatments are often associated with increased risks of pain, swelling, bleeding and, recurrence of malignancy.

The aim of this review was to identify the optimal treatment option for oral mucosal leukoplakia. The current review included all studies focusing on the treatment of oral mucosal leukoplakia and published between 2016 and 2021.

The findings of this study showed that laser surgical treatment of oral mucosal verrucous leukoplakia resulted in statistically significant advantages in the intra- and postoperative periods.

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About the authors

Viktoriya V. Morozova

I.M. Sechenov First Moscow State Medical University (Sechenov University)

Email: mrzvanika@gmail.com
ORCID iD: 0000-0003-0642-2813

intern

Russian Federation, Moscow

Svetlana V. Tarasenko

I.M. Sechenov First Moscow State Medical University (Sechenov University)

Author for correspondence.
Email: prof_tarasenko@rambler.ru
ORCID iD: 0000-0001-8595-8864
SPIN-code: 3320-0052

MD, Dr. Sci. (Med.), Professor

Russian Federation, Moscow

Michail A. Stepanov

I.M. Sechenov First Moscow State Medical University (Sechenov University)

Email: doctor.stepanov@gmail.com
ORCID iD: 0000-0002-1872-9487
SPIN-code: 6524-5665

MD, Cand. Sci. (Med.), assistant professor

Russian Federation, Moscow

Sergey A. Kalinin

I.M. Sechenov First Moscow State Medical University (Sechenov University)

Email: medikas97@mail.ru
ORCID iD: 0000-0002-0310-1873

intern

Russian Federation, Moscow

Anna G. Maltseva

I.M. Sechenov First Moscow State Medical University (Sechenov University)

Email: ann.agent6@gmail.com
ORCID iD: 0000-0003-0912-6796

student

Russian Federation, Moscow

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