Email this article 
Study of the influence of different methods of application of Metrogyl Denta gel on the microbiota of periodontal pockets in periodontitis
- Authors: Morozov D.I.1, Volkov A.G.2, Olesov E.E.1, Dikopova N.Z.2, Trefilova Y.A.3
-
Affiliations:
- Burnazyan Federal Medical Biophisical Center
- I.M. Sechenov First Moscow State Medical University Moscow (Sechenov University)
- A.I. Evdokimov Moscow State Medical and Dental University
- Issue: Vol 25, No 1 (2021)
- Pages: 42-47
- Section: Clinical Investigation
- URL: https://rjdentistry.com/1728-2802/article/view/89233
- DOI: https://doi.org/10.17816/1728-2802-2021-25-1-42-47
- ID: 89233
Cite item
Open Access
Access granted
Abstract
BACKGROUND: One of the most popular antibacterial drugs used in periodontology is Metrogil Denta gel. In recent years, it is most often prescribed as a means of local antibacterial therapy. However, there is practically no information about the use of Metrogil Denta gel ultraphonophoresis in the treatment of periodontal tissue diseases. Therefore, the development of the Metrogil Denta gel ultraphonophoresis technique and the study of its effectiveness in inflammatory periodontal diseases has significant theoretical and practical interest.
AIM: This study aimed to explore the influence of various methods of using Metrogyl Denta gel on the microbiota of the periodontal pockets in periodontitis.
MATERIALS AND METHODS: In the first group (main), composed of 20 patients with a diagnosis of moderate periodontitis, the treatment procedures included high-frequency ultrasound and application of antibacterial preparation of Metrogyl Denta gel for the periodontal tissue (ultraphonophoresis of Metrogyl Denta gel). In the second group (control), composed of 20 patients with a diagnosis of moderate periodontitis, phonophoresis was not prescribed, and Metrogyl Denta gel was applied into the surface of the gums of the upper and lower jaw two times a day for 10 days.
RESULTS: Contents of the pathological periodontal pockets were examined twice: first after dental plaque removal in patients with periodontitis of the main and control groups and then after 10 ultraphonophoresis procedures using Metrogyl Denta gel as a contact medium in the study group or after 10 days of Metrogyl Denta gel applications in the control group. Data analysis revealed that ultraphonophoresis of Metrogyl Denta gel has a more pronounced antibacterial effect in comparison with the injection of this drug.
CONCLUSIONS: The combined effect of high-frequency ultrasound and Metrogyl Denta gel makes it possible to create a drug reserve in the periodontal tissues.
Full Text
About the authors
Dmitry I. Morozov
Burnazyan Federal Medical Biophisical Center
Email: info@stomatologclub.ru
Russian Federation, Moscow
Alexander G. Volkov
I.M. Sechenov First Moscow State Medical University Moscow (Sechenov University)
Email: parodont@inbox.ru
ORCID iD: 0000-0003-2674-1942
MD, Dr. Sci. (Med.), Professor
Russian Federation, 2, Bolshaya Pirogovskaya str., 119991, MoscowEgor E. Olesov
Burnazyan Federal Medical Biophisical Center
Email: olesov_georgiy@mail.ru
MD, Dr. Sci. (Med.), Professor
Russian Federation, MoscowNataliya Zh. Dikopova
I.M. Sechenov First Moscow State Medical University Moscow (Sechenov University)
Author for correspondence.
Email: zubnoy-doctor@yandex.ru
ORCID iD: 0000-0002-4031-2004
MD, Cand. Sci. (Med.), assistant professor
Russian Federation, 2, Bolshaya Pirogovskaya str., 119991, MoscowYulia A. Trefilova
A.I. Evdokimov Moscow State Medical and Dental University
Email: zubnoy-doctor@yandex.ru
ORCID iD: 0000-0002-0443-4071
Russian Federation, Moscow
References
- Kovalevskij АМ, Potoczkaya AV, Podberyozkina LA, et al. Possibilities of application of physical methods in complex treatment of inflammatory periodontal diseases (literature review). The dental Institute. 2019;(2):90–93. (In Russ).
- Lyubomirskiy GB, Redinova TL. Microcirculatory changes in periodontal tissues of patients with periodontitis in the dynamics of physical therapy. Parodontologiya. 2020;25(1):63–70. (In Russ). doi: 10.33925/1683-3759-2020-25-1-63-70
- Makeeva IM, Volkov AG, Daurova FY, et al. Apparatnye metody lechenija v stomatologii: uchebnoe posobie. Moscow; 2017. (In Russ).
- Volkov AG, Prikuls VF, Dikopova NZh, et al. The study on the impact of various types of currents on root canal microbiota. Stomatology. 2019;98(2):37–41. (In Russ). doi: 10.17116/stomat20199802137
- Kazantseva IA, Turdalieva FM. Izuchenie jeffektivnosti primenenija "Jodo-glikol' pasty Neo" v sravnenii s "Metrogil denta" v kompleksnom lechenii pacientov s hronicheskim parodontitom. Lekarstvennyi vestnik. 2019;13(3):27–31. (In Russ).
- Krivchikova AS, Sadkova EE. Sravnitel'nyj analiz antimikrobnyh preparatov dlja lechenija hronicheskogo generalizovannogo parodontita. Bulletin of Medical Internet Conferences. 2015;5(10): 1215–1216. (In Russ).
- Efanov OI, Tsarev VN, Volkov AG, et al. Ocenka antibakterial'noj aktivnosti apeks-foreza. Stomatology. 2006;85(5):20. (In Russ).
- Efanov OI, Tsarev VN, Volkov AG, et al. Antibaterial effects of zinc during apex-phoresis. Russian Journal of Dentistry. 2012;(1):5–9. (In Russ).
- Efanov OI, Tsarev VN, Nosik AS, et al. In vitro study of the antibacterial activity of apex-phoresis using silver-copper electrode. Russian Journal of Dentistry. 2006;(4):1–6. (In Russ).
- Lashko IS, Tsarev VN, Olesov EE, et al. Comparative microbiological research of sensitivity of microflora of the oral cavity to the drugs krezacin denta and metrogyl denta. Russian Journal of Dentistry. 2019;23(3–4):149–152. (In Russ). doi: 10.18821/1728-2802-2019-23-3-4-149-152
Supplementary files
