Clinical efficiency of ultraphonophoresis of Metrogyl Denta gel in mild periodontitis

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Abstract

BACKGROUND: Periodontal diseases are one of the most common in dentistry. Along with the complications of caries, periodontitis is one of the causes of tooth loss. In the etiology of this disease, the leading role is played by the microbial factor, as well as microcirculatory disorders in periodontal tissues. The complex mechanism of periodontitis development involves a comprehensive treatment approach aimed at different links in the pathogenesis of the development of this disease. Among the numerous physical factors used in the treatment of periodontal diseases, ultraphonophoresis, which combines the effects of ultrasound and a medicinal substance, is not widely used. The study of the effectiveness of the use of Metrogil Denta gel ultraphonophoresis in the treatment of inflammatory periodontal diseases is of considerable scientific and practical interest.

AIM: This study aimed to investigate the effect of ultraphonophoresis of gel on the clinical course of chronic generalized periodontitis of moderate severity.

MATERIALS AND METHODS: Sixty patients (aged 31–62) with chronic generalized periodontitis of moderate severity were examined and treated. In the main group (n=30), treatment included high-frequency ultrasound and antibacterial preparation of Metrogyl Denta gel applied to the periodontal tissue (ultraphonophoresis of Metrogyl Denta gel). In the control group (n=30 patients), Metrogyl Denta gel was injected into the periodontal tissue.

RESULTS: Application of Metrogyl Denta gel for moderate periodontitis did not improve local blood circulation. Six months after treatment, nearly half of the examined patients showed signs of inflammation, which was accompanied by a worsening of periodontal index (PI), Schiller–Pisarev tests results, and rheography finding. Twelve months after treatment, 63% of the patients developed complications.

CONCLUSIONS: There was further deterioration in the clinical and functional parameters. After ultraphonophoresis of Metrogyl Denta gel, there was a decrease in the readings of the Schiller–Pisarev test, PI, and normalization of the qualitative and quantitative indicators of the rheoparodontogram, which indicated a decrease in inflammation and activation of local blood circulation in the periodontium. In the long term after treatment, despite the increase in hygiene index, the relative stability of clinical and functional parameters was maintained. Even a year after treatment, the level of indicators did not reach the level obtained before treatment.

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About the authors

Alexander G. Volkov

I.M. Sechenov First Moscow State Medical University Moscow (Sechenov University)

Email: parodont@inbox.ru
ORCID iD: 0000-0003-2674-1942

MD, Dr. Sci. (Med.), Professor

Russian Federation, 2, Bolshaya Pirogovskaya str., 119991, Moscow

Dmitry I. Morozov

Burnasyan Federal Medical Biophysical Center

Email: info@stomatologclub.ru
Russian Federation, Moscow

Nataliya Zh. Dikopova

I.M. Sechenov First Moscow State Medical University Moscow (Sechenov University)

Author for correspondence.
Email: zubnoy-doctor@yandex.ru
ORCID iD: 0000-0002-4031-2004

MD, Cand. Sci. (Med.), assistant professor

Russian Federation, 2, Bolshaya Pirogovskaya str., 119991, Moscow

Egor E. Olesov

Burnasyan Federal Medical Biophysical Center

Email: olesov_georgiy@mail.ru

MD, Dr. Sci. (Med.), Professor

Russian Federation, Moscow

Alexandr I. Sinyakov

Burnasyan Federal Medical Biophysical Center

Email: olesova@implantat.ru
Russian Federation, Moscow

References

  1. Osipova MV. Analysis of prevalence of periodontal diseases. Scientific notes of the I.P. Pavlov St. Petersburg State Medical University. 2012;3(19):118–122. (In Russ).
  2. Abdulmedzhidova DM. Risk factors for periodontal disease in adults. Russian Journal of Dentistry. 2017;21(2):72–75. (In Russ). doi: 10.18821/1728-28022017;21(2)72-75
  3. Lyubomirskiy GB, Redinova TL. Microcirculatory changes in periodontal tissues of patients with periodontitis in the dynamics of physical therapy. Parodontologiya. 2020;25(1):63–70. (In Russ). doi: 10.33925/1683-3759-2020-25-1-63-70
  4. Akhmedbaeva SS, Volkov AG, Dikopova NZh, et al. The use of ultrasound and ozone therapy in the complex treatment of periodontitis. Russian Journal of Dentistry. 2020;24(2):74–78. (In Russ). doi: 10.17816/1728-2802-2020-24-2-74-78
  5. Lashko IS, Tsarev VN, Olesov EE, et al. Comparative microbiological research of sensitivity of microflora of the oral cavity to the drugs krezacin denta and Metrogyl denta. Russian Journal of Dentistry. 2019;23(3–4):149–152. (In Russ). doi: 10.18821/1728-2802-2019-23-3-4-149-152

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