Optimization of healing in patients with odontogenic phlegmon of the maxillofacial region

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Aim. This study aims to increase the efficiency of the wound process in patients with odontogenic phlegmons of the maxillofacial region by using energotropic and antioxidant agents. Material and methods. The clinical study included 42 patients with odontogenic phlegmons of the maxillofacial region. The patients were divided into two groups: comparison group (patients received traditional treatment) and main group (patients received treatment with Cytoflavin in the treatment regimen). Results. In the main group, the appearance of the first granulations occurred 2.1 times faster (on average on the 3rd day) in comparison with the granulation tissue in patients of the comparison group. Signs of edge epithelialization of wounds appeared almost 3 days earlier (on average on the 6th day) in the main group than in the comparison group; on the 7th day, secondary sutures were already applied, which was 1.6 times faster than the same parameter group 2, clearly suggesting the acceleration of reparative processes. Conclusion. The dynamics of clinical manifestations indicates the comparative effectiveness of using Cytoflavin as part of complex therapy. This finding is confirmed by the accelerated terms of wound healing, the appearance of granulations, epithelialization of the wound edges, and the imposition of secondary sutures.

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About the authors

O. V. Shvets

Kuban State Medical University of the Ministry of Health of Russia

Email: corpus@ksma.ru
Russian Federation, Krasnodar

Tatiana V. Gaivoronskaya

Kuban State Medical University of the Ministry of Health of Russia

Author for correspondence.
Email: corpus@ksma.ru

MD, Dr. Sci. (Med.), Prof., Head of the Department of Surgical Dentistry and Maxillofacial Surgery, Kuban State Medical University

Russian Federation, Krasnodar

E. E. Esaulenko

Kuban State Medical University of the Ministry of Health of Russia

Email: corpus@ksma.ru
Russian Federation, Krasnodar

N. I. Bykova

Kuban State Medical University of the Ministry of Health of Russia

Email: corpus@ksma.ru
Russian Federation, Krasnodar


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Supplementary files

Supplementary Files
1. Dynamics of the clinical characteristics of the wound process in patients with phlegmons of the maxillofacial region against the background of traditional treatment and with additional antioxidant correction (Me (Q1 / Q3)). * - statistically significant differences between the indicators of the comparison group and the main group (p <0.05).

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